My lad runs a DMC Alien system on his bike for MX, its really good in the low/mids but lacks top end power some.
DMC Alien likes the stock needle to be at its highest setting to make it work well in the lower register.
We tried a Vitos blue needle but it was crap, so went back to the stock one.
I can't remember what main we used but I think it was around 290- 300, a plug chop will tell if you have it right.
Do a plug chop also at 1/2 to 3/4 throttle to see if the needle is in the right place as well.
I should add the we run castor based oil at 25:1, and in warm climates, which may explain the big main jet.